Few studies have prospectively evaluated the progression of chronic kidney disease (CKD) in children and adolescents, as well as factors associated with progression. A multicenter observational study conducted as part of the NIH-funded Chronic Kidney Disease in Children study found characterization and modeling of risk factors for CKD progression can be used to predict the extent to which factors such as proteinuria, hypoabluminemia, blood pressure, dyslipidemia and anemia -- either alone or in combination -- would shorten the time to renal replacement therapy or 50% decline in GFR in children with chronic kidney disease.Bradley Warady, MD is here to discuss chronic kidney disease in children and adolescents.
