A recent Northwestern Medicine study published in Nature Gene Therapy has shown that the degeneration of brain motor neurons in ALS is not merely a byproduct of the spinal motor neuron degeneration, and is a target for future treatments for the disease. Lead study author, P. Hande Ozdinler, PhD, associate professor of Neurology and director of the Ozdinler Lab in the Les Turner ALS Center at Northwestern Medicine, explains the importance of these findings.