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EP 159 - Prevention and Reversal of the Cognitive Decline of Alzheimer's

From the Show: Dr. Taz Show
Summary: Alzheimer’s disease can and should be prevented. Dr. Dale Bredesen explains how.
Air Date: 12/31/19
Duration: 34:12
Host: Dr. Taz
Guest Bio: Dale Bredesen, MD
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Dale Bredesen, MD, received his undergraduate degree from Caltech and his medical degree from Duke. He served as Resident and Chief Resident in Neurology at UCSF, then was postdoctoral fellow in the laboratory of Nobel laureate Prof. Stanley Prusiner. He was a faculty member at UCLA from 1989-1994, then was recruited by the Burnham Institute to direct the Program on Aging. In 1998 he became the Founding President and CEO of the Buck Institute for Research on Aging, and Adjunct Professor at UCSF; then in 2013 he returned to UCLA as the Director of the Easton Center for Alzheimer’s Disease Research.

The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer’s disease and other neurodegenerative conditions, leading to the publication of over 220 research papers. He established the ADDN (Alzheimer’s Drug Development Network) with Dr. Varghese John in 2008, leading to the identification of new classes of therapeutics for Alzheimer’s disease. He and his group developed a new approach to the treatment of Alzheimer’s disease, and this approach led to the discovery of sub-types of Alzheimer’s disease, followed by the first description of reversal of symptoms in patients with MCI and Alzheimer’s disease, with the ReCODE (reversal of cognitive decline) protocol, published in 2014, 2016, and 2018.

His book, The End of Alzheimer’s, is a New York Times Bestseller. 
  • Book Title: The End of Alzheimer's
  • Guest Facebook Account: https://www.facebook.com/drdalebredesen/
  • Guest Twitter Account: @DrDaleBredesen
EP 159 - Prevention and Reversal of the Cognitive Decline of Alzheimer's
In recent years, Alzheimer's disease has affected more and more people and it’s hitting at an earlier age. It’s the third leading cause of death in the United States. Two-thirds of Alzheimer's patients are women.

As recently as a few years ago, there was no hope for people diagnosed with Alzheimer's disease. However, recent research shows that those who come in early can have a very good prognosis. The key is prevention and early detection. 

In addition to genetic testing, adults age 45 and older should have conversations with their physician about lifestyle factors that can cause Alzheimer’s. They should also start getting regular cognoscopies, a test used to evaluate the risk factors that can cause neuro-degenerative diseases like Alzheimer's. 

Dr. Dale Bredesen explains that a healthy plant-based diet that’s mildly ketogenic, stress management, and regular sleep patterns can help prevent Alzheimer’s and other neuro-degenerative diseases.

Listen as Dr. Dale Bredesen joins Dr. Taz to discuss the prevention of Alzheimer’s disease.