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Measles Outbreak: How Can You Protect Your Children?

From the Show: Healthy Children
Summary: A measles outbreak that began at Disneyland in California has grown to more than 50 confirmed cases in multiple states.  
Air Date: 1/28/15
Duration: 10
Host: Melanie Cole, MS
Guest Bio: Kathryn M. Edwards, MD
edwardsKathryn M. Edwards, MD, the Sarah H. Sell and Cornelius Vanderbilt Professor of Pediatrics and directs the Vanderbilt Vaccine Research Program. She graduated from the University of Iowa College of Medicine and completed her pediatric residency and infectious disease fellowship at Northwestern University and her postdoctoral training in Immunology at Rush Medical School in Chicago. Dr. Edwards joined the Vanderbilt Vaccine Program in 1980 and has conducted many pivotal vaccine studies since that time. She has had an extensive experience in leading NIH-funded multicenter initiatives; in designing, conducting, and analyzing pivotal Phase I, II, and III clinical studies on vaccines and therapeutics; in facilitating networking with basic and clinical investigators with a wide range of interests and expertise; and in mentoring many of the young investigators who currently work within the research unit.

She initially focused her efforts on conducting studies of Haemophilus influenzae, type b capsular polysaccharide protein conjugate vaccines in infants within the NIH-funded VTEU. In 1985, she received NIH-funding to conduct a comparative influenza efficacy trial of live attenuated and inactivated influenza vaccines in 3000 children and adults each year for five years. These studies documented the safety and efficacy of both inactivated and live attenuated influenza vaccines in a very large number of children and adults. In 1990, she coordinated the NIH-funded Multicenter Acellular Pertussis Trial comparing 13 different acellular pertussis vaccines produced by different manufacturers throughout the world with two whole cell pertussis vaccines produced in the United States. In these studies, more than 2000 infants were enrolled at six VTEU sites in the United States, and the safety and immunogenicity of the vaccines were compared. In the late 1990s, she conducted additional studies on bacterial vaccines when she studied pneumococcal conjugate vaccines in 260 young infants and determined their role in preventing colonization and disease.

In 1998, Dr. Edwards was awarded a contract from the Centers for Disease Control and Prevention (CDC) to conduct active population-based surveillance to monitor the impact of newly licensed vaccines. In these surveillance efforts, she and her colleagues have determined the burden of many important viral respiratory pathogens, including influenza, RSV, PIV, rhinovirus, coronavirus, and hMPV in both the inpatient and outpatient settings.

For the past decade, Dr. Edwards has also led the CDC-funded Center for Immunization Safety Assessment (CISA) site at Vanderbilt where she and her colleagues assess adverse events associated with vaccines in subjects of all ages. Dr. Edwards was also awarded a CDC contract in 2011 to conduct comprehensive pneumonia surveillance studies in over 2000 adults and children admitted to Vanderbilt adult and pediatric hospitals and at one other community hospital in Nashville.

Dr. Edwards is PI for the current NIH-funded VTEU contract. Dr. Edwards has served on several CDC, NIH, WHO, and IDSA committees. In 2006, she received the IDSA Mentor Award for her exceptional mentoring and in 2014 received the Maureen Andrews Mentoring Award from the Society for Pediatric Research. In 2008 she was elected to the Institute of Medicine of the National Academy of Sciences.
Measles Outbreak: How Can You Protect Your Children?
Measles is a highly contagious respiratory disease that spreads easily through the air or on infected surfaces.

It causes rash, high fever, cough, runny nose and red watery eyes. People who are infected with measles can spread the virus up to four days before they develop symptoms.

Vaccines are one of the most important ways parents can protect their children from very real diseases that exist in our world.

Kathryn M. Edwards, MD, discusses this latest measles outbreak and just how important it is for you to get your child vaccinated.
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