Assuming philip is required, and sarrel is required, the following results were found.

Hysterectomy: Estrogen Therapy Saves Lives
Researchers estimate 50,000 deaths could have been prevented if women who had hysterectomies had estrogen hormonal therapy.
Hormone Therapy & Your Heart Health: Are You at Risk for Cardiovascular Disease?
Recent research shows you may be able to reduce your risk of heart disease by taking estrogen.
Should You Be Removing Your Ovaries & Fallopian Tubes?
The "Angelina Effect" is spreading again after Angelina Jolie recently decided to remove her ovaries and fallopian tubes due to an elevated risk of cancer.

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